Speciality
Spotlight

 




 


Respiratory
– Pulmonary – Asthma



 

 





Chronic Eosinophilic Pneumonia

   

  • E Marchand, and the Groupe d”Etudes et de Recherche sur les Maladies “Orphelines” Pulmonaries (GERM “O”P) (Hopital Cardiovasculaire et Pneumologique Louis Pradel, Lyon, France; et al). 

    Idiopathic Chronic Eosinophilic Pneumonia: A
    Clinical and Follow-up Study of 62 cases. 

    Medicine 77:299-312, 1998.

      


    Idiopathic chronic eosinophilic pneumonia (CEP), a rare disorder of unknown causes. 

      


    Of 62 carefully selected patients with CEP, 46 were followed up for more than 1 year. All patients had bronchoalveolar lavage (BAL) eosinophilia. Sixty-eight percent of the patients had a ventilatory defect, which was obstructive in 35% and restrictive in 32%. Open lung biopsy was performed in only 6.5% of the patients. 

      


    All but 1 patient received oral corticosteroid therapy, at a mean initial dose of 0.97mg/kg per day of prednisone. All treated patients had rapid subjective improvement. Eighty-two percent were improved within 48 hours. Within 1 week of treatment, 49 patients underwent chest radiography, which showed disappearance of initial opacities in 69.4%. Forty-eight relapses occurred in 30 (48%) patients.

       


 



 

 

Speciality Spotlight

 

 

Chronic Eosinophilic Pneumonia
   

  • E Marchand, and the Groupe d”Etudes et de Recherche sur les Maladies “Orphelines” Pulmonaries (GERM “O”P) (Hopital Cardiovasculaire et Pneumologique Louis Pradel, Lyon, France; et al). 
    Idiopathic Chronic Eosinophilic Pneumonia: A Clinical and Follow-up Study of 62 cases. 
    Medicine 77:299-312, 1998.
      
    Idiopathic chronic eosinophilic pneumonia (CEP), a rare disorder of unknown causes. 
      
    Of 62 carefully selected patients with CEP, 46 were followed up for more than 1 year. All patients had bronchoalveolar lavage (BAL) eosinophilia. Sixty-eight percent of the patients had a ventilatory defect, which was obstructive in 35% and restrictive in 32%. Open lung biopsy was performed in only 6.5% of the patients. 
      
    All but 1 patient received oral corticosteroid therapy, at a mean initial dose of 0.97mg/kg per day of prednisone. All treated patients had rapid subjective improvement. Eighty-two percent were improved within 48 hours. Within 1 week of treatment, 49 patients underwent chest radiography, which showed disappearance of initial opacities in 69.4%. Forty-eight relapses occurred in 30 (48%) patients.
       

 

 

By |2022-07-20T16:41:51+00:00July 20, 2022|Uncategorized|Comments Off on Chronic Eosinophilic Pneumonia

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