Speciality
Spotlight

 




 


Respiratory – Pulmonary – Asthma


 

 





Intestitial
Lungs Diseases

   

  • Risk Factors/Epidemiology

    RW Tobin, II CE Pope, CA Pellegrini, et al (Univ of Washington, Seattle)


    Increased Prevalence of Gastroesophageal Reflux in Patiens with Idiopathic Pulmonary Fibrosis.


    Am J Respir Crit Care Med 158: 1804-1808, 1998.

      


    Idiopathic pulmonary fibrosis refers to those cases of interstitial lung disease with no apparent initiating inflammatory event. Gastroesophageal reflux (GER), which has been linked to other airway disorders, was proposed as a possible initiating factor of IPF and patients with IPF were studied to determine their prevalence of GER.

        


    This fascinating though small study explores a potential cause of IPF, a lethal lung disease. Although the use corticosteroids and other immunosuppressive agents has been widespread in treatment of patients with IPF, there is a growing consensus that these medications are usually not effective. IPF tends to affect middle-aged to older adults, which are also the age groups prone to GER. This study by Tobin et al includes a relatively small number of subjects, the results of which need to be confirmed in additional studies on large groups of patients.

        


    In the meantime, it is obvious that investigation for possible GER are reasonable for patients with progressive IPF and if found the GER should be treated aggressively.

       


 



 

 

Speciality Spotlight

 

 

Intestitial Lungs Diseases
   

  • Risk Factors/Epidemiology
    RW Tobin, II CE Pope, CA Pellegrini, et al (Univ of Washington, Seattle)
    Increased Prevalence of Gastroesophageal Reflux in Patiens with Idiopathic Pulmonary Fibrosis.
    Am J Respir Crit Care Med 158: 1804-1808, 1998.
      
    Idiopathic pulmonary fibrosis refers to those cases of interstitial lung disease with no apparent initiating inflammatory event. Gastroesophageal reflux (GER), which has been linked to other airway disorders, was proposed as a possible initiating factor of IPF and patients with IPF were studied to determine their prevalence of GER.
        
    This fascinating though small study explores a potential cause of IPF, a lethal lung disease. Although the use corticosteroids and other immunosuppressive agents has been widespread in treatment of patients with IPF, there is a growing consensus that these medications are usually not effective. IPF tends to affect middle-aged to older adults, which are also the age groups prone to GER. This study by Tobin et al includes a relatively small number of subjects, the results of which need to be confirmed in additional studies on large groups of patients.
        
    In the meantime, it is obvious that investigation for possible GER are reasonable for patients with progressive IPF and if found the GER should be treated aggressively.
       

 

 

By |2022-07-20T16:41:52+00:00July 20, 2022|Uncategorized|Comments Off on Intestitial Lungs Diseases

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