Microbiology

Microbiology

  

• Guzman
  Valdivia Gomez G, Guerrero TS, Lluck MC, et al [
  Mexican Inst of Social Security [IMSS], Mexico City]
  
  Effectiveness of Collagen-Gentamicin Implant
  for Treatment of – Dirty – Abdominal Wounds
  
  World
  J Surg 23: 123-127, 1999
  
       
  
  -
  Dirty – abdominal wounds are associated with a high
  risk of infection, despite
  preventive measures. Leaving
  the wound open with daily dressing avoids delay in
  diagnosis and reduces the chances of serious
  complications. The
  effect of a collagen gentamicin implant in such wounds
  with primary closure was studied.
  
        
  
  73
  patients undergoing surgery on the lower GI tract and
  having ‘dirty’ wounds were randomly divided into 2
  groups. Group
  `A’ was managed with local cleansing and systemic
  preventive therapy. Group `B’, a collagen gentamicin implant was put in and the wound
  closed primarily with
  the same systemic therapy.
  
      
  
  66
  patients completed the study. Group A had infection
  rate of 44%. Group B had 9% only.
  
       
  
  The
  mean wound healing time was 15 days [ Gr. A] versus 10
  days [Gr.B]. 43% of Gr. B had a transient wound
  discharge of serous fluid. 
  All infections in Gr. A were polymicrobial
  against monomicrobial in Gr. B.
  
       
  
  The
  collagen-gentamicin implant provides a significant
  improvement in the management of ‘dirty’ abdominal
  wounds.
  
        

• Delgado-Rodriguez
  M, Gomez-Ortega A, Llorca J, et al [Univ of Cantabria,
  Santander, Spain; Hosp General Ciudad de Jain, Spain;
  Univ of La Laguna Tenerife, Spain; et al]
  
  Nosocomial Infection, Indices of Intrinsic
  Infection Risk, and in-Hospital Mortality in General
  Surgery
  
  J
  Hosp Infect 41: 203-211, 1999
  
       
  
  Two
  indexes of intrinsic infection risk have been proposed
  to control for baseline differences among patients
  from different hospital services and make appropriate
  comparisons and NNIS index.