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Speciality Spotlight
Renal
Transplant
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TH Mathew, for the Tricontinental Mycophenolate Mofetil Renal Transplantation Study group (Queen Elizabeth Hosp, Woodville, South Australia):
A blinded, long-term, randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation.
Transplantation 65: 1450-1454, 1998.
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A Zaidi, M Schmoeckel, F Bhatti, et al (Univ of Cambridge, England; Imutran Ltd, Cambridge, England; Papworth Hosp., Cambridge, England):
Life supporting pig-to-primate renal xenotransplantation using genetically modified donors.
Transplantation 65: 1584 – 1590, 1998.
In this pig-to-primate transplant model, xenograft kidneys from human decay-accelerating factor transgenic pigs show prolonged survival. The experience includes no episodes of hyperacute rejection of transgenic kidneys which may also be protected against acute vascular rejection. The findings also demonstrate the basic physiologic compatibility between a pig and a non-human primate.
