Speciality
Spotlight

   




   

Surgery


   

 





Respiratory

  

  • MH
    Desai, R Mlcak, J Richardson et al,1998 
    (Univ of Texas, Galveston; Shriners Burns Inst,
    Galveston, Tex);   

    Reduction
    in Mortality in Pediatric Patients With Inhalation
    Injury with Aerosolized Heparin/N-acetylcysteine
    Therapy
    .    

    J Burn
    Care Rehabil  19:210-212,

         

    Smoke
    inhalation injury is a major cause of death after
    burns.The injuries are associated with fibrin cast
    deposition in the airways as well as progressive
    carbon dioxide retention resulting from a ball valve
    effect.

         

    Based on promising results on animal studies, a
    combination of aerosolized heparin and acetylcysteine
    was evaluated for the treatment of smoke inhalation
    injury in children.

         

    The
    above regime reduced mortality, atelectasis and the
    need for reintubation.
    This mode of therapy addresses the
    pathophysiological mechanics of inhalation injury by
    reducing free radical ions and inhibiting fibrin cast
    formation.

         



 

   

Speciality Spotlight

   

   
Surgery
   

 

Respiratory
  

  • MH Desai, R Mlcak, J Richardson et al,1998  (Univ of Texas, Galveston; Shriners Burns Inst, Galveston, Tex);   
    Reduction in Mortality in Pediatric Patients With Inhalation Injury with Aerosolized Heparin/N-acetylcysteine Therapy.    
    J Burn Care Rehabil  19:210-212,
         
    Smoke inhalation injury is a major cause of death after burns.The injuries are associated with fibrin cast deposition in the airways as well as progressive carbon dioxide retention resulting from a ball valve effect.
         
    Based on promising results on animal studies, a combination of aerosolized heparin and acetylcysteine was evaluated for the treatment of smoke inhalation injury in children.
         
    The above regime reduced mortality, atelectasis and the need for reintubation. This mode of therapy addresses the pathophysiological mechanics of inhalation injury by reducing free radical ions and inhibiting fibrin cast formation.
         

 

By |2022-07-20T16:43:43+00:00July 20, 2022|Uncategorized|Comments Off on Respiratory

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