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Speciality Spotlight
Enteric
Infections
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D Bieber, SW Ramer, C-Y Wu, et al (Stanford Univ, Calif)
Type IV Pili, Transient Bacterial Aggregates, and Virulence of Enteropathogenic Escherichia Coli.
Science 280:2114-2118, 1998.
Enteropathogenic Escherichia-coli (EPEC) is an important cause of childhood diarrhoea. It is a type IV pilus-producing organism. Type IV pilus called the bundle-forming pilus (BFP) is necessary for the development of localized adherence and autoaggression.