Speciality
Spotlight

 




 


Gastroenterologist


     

 





Gall bladder

    

  • CM
    Hollands, FJ Rivera-Pedrogo, R Gonzalez-Vallina, et al (Miami Children’s Hosp,
    Fla)

    Ileal exclusion for Byler’s disease: An alternative surgical aprooach with promising early results for
    pruritus.


    J Pediatr Surg 33:220-224, 1998.

       


    Progressive familial intrahepatic cholestasis (PFIC) – also called Byler’s disease – is an uncommon cause of hepatocellular
    cholestasis. Affected children have intermittent, painless jaundice. Intense pruritus disproportionate to the degree of hyperbilirubinemia can lead to self-mutilation by scratching. Good results have been achieved with liver transplantation and cutaneous biliary diversion procedures, both of which have their complications. Ileal exclusion or bypass procedures offer some important potential advantages over these approaches.

    Promising early results are reported with this terminal ileal exclusion procedure for patients with
    PFIC. The procedure offers good relief from pruritus with a stoma-free
    “biliary diversion” that is completely reversible. Longer follow-up is needed, including evaluation of the effects of growth and development, liver function and liver histology.

     

  • Leitzmann MF, Giovannucci EL, Rimm EB, et al [Harvard School of Public Health, Boston; Harvard Med School, Boston; Brigham and Women’s Hosp, Boston]


    The Relation of Physical Activity to Risk for Symptomatic Gallstone Disease in Men


    Ann Intern Med 128: 417-425, 1998

    This article involves a study of 51,529 men in The Health Professionals follow-up Study in American males of the age group of 40 to 75 years. Between the year 1986-1994 a total of 45,813 were taken as a sample.

     


    828 symptomatic gallstones disease subjects were detected and analyzed from the view point of physical activity. Endurance training revealed maximum protection from gallstones disease in the age group below 65 years. Those with sedentary life style had a higher level of disease.

     


    It is suggested that all subjects above 40 years should begin a vigorous exercise programme. Effect in women needs to be studied.

        

 



 

 

Speciality Spotlight

 

 
Gastroenterologist
     

 

Gall bladder
    

  • CM Hollands, FJ Rivera-Pedrogo, R Gonzalez-Vallina, et al (Miami Children’s Hosp, Fla)
    Ileal exclusion for Byler’s disease: An alternative surgical aprooach with promising early results for pruritus.
    J Pediatr Surg 33:220-224, 1998.
       
    Progressive familial intrahepatic cholestasis (PFIC) – also called Byler’s disease – is an uncommon cause of hepatocellular cholestasis. Affected children have intermittent, painless jaundice. Intense pruritus disproportionate to the degree of hyperbilirubinemia can lead to self-mutilation by scratching. Good results have been achieved with liver transplantation and cutaneous biliary diversion procedures, both of which have their complications. Ileal exclusion or bypass procedures offer some important potential advantages over these approaches.
    Promising early results are reported with this terminal ileal exclusion procedure for patients with PFIC. The procedure offers good relief from pruritus with a stoma-free “biliary diversion” that is completely reversible. Longer follow-up is needed, including evaluation of the effects of growth and development, liver function and liver histology.
     

  • Leitzmann MF, Giovannucci EL, Rimm EB, et al [Harvard School of Public Health, Boston; Harvard Med School, Boston; Brigham and Women’s Hosp, Boston]
    The Relation of Physical Activity to Risk for Symptomatic Gallstone Disease in Men
    Ann Intern Med 128: 417-425, 1998
    This article involves a study of 51,529 men in The Health Professionals follow-up Study in American males of the age group of 40 to 75 years. Between the year 1986-1994 a total of 45,813 were taken as a sample.
     
    828 symptomatic gallstones disease subjects were detected and analyzed from the view point of physical activity. Endurance training revealed maximum protection from gallstones disease in the age group below 65 years. Those with sedentary life style had a higher level of disease.
     
    It is suggested that all subjects above 40 years should begin a vigorous exercise programme. Effect in women needs to be studied.
        

 

 

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