Schenk BE, Kuipers EJ, Klinkenberg-Knol EC, et al [ Free Univ Hosp, Amsterdam; ‘t Lange Land Hosp, Zoetermeer, The Netherlands; Bronovo Hosp Den Haag, The Netherlands]
Omeprazole as a Diagnostic Tool in Gastroesophageal Reflux Disease
AM J Gastroenterol 92: 1997-2000, 1997
Gastroesophageal reflux disease [ GERD] can be confused with other disorders associated with retrosternal discomfort eg. Heart burn. If 40 mgm of omeprazole given for 2 weeks relieves symptoms a diagnosis of GERD can be made without recourse to endoscopy.