Valve Disease Haemodialysis
- Cirit M, Ozkahya M, Soydas Cinar C, et al (Ege Univ, Izmir, Turkey)
Disappearance of Mitral and Tricuspid Regurgitation in Haemodialysis Patients After Ultrafiltration
Nephrol Dial Transplant 13: 389-392, 1998
Patients with valvular regurgitation who are undergoing dialysis have a poor prognosis. Controlling the resulting volume overload and cardiac dilatation with ultrafiltration may reduce the functional aggravation.
In 21 patients (9 females) undergoing haemodialysis, Doppler echocardiography detected mitral and tricuspid regurgitation. All patients received intensified ultrafiltration (UF) during dialysis until blood pressure and heart size became normal.
After UF regurgitation improved in all, mitral regurgitation disappeared in 13 and tricuspid regurgitation disappeared in 14. Significant changes also occurred in other parameters, such as mean arterial blood pressure, heart size, left atrial and ventricular pressures and diameters of mitral annulus; left ventricular ejection fraction increased after treatment in all patients but remained below 50% in 11 patients.
Ultrafiltration in dialysis patients can ameliorate valvular regurgitation and significantly improve cardiac dimensions and blood pressure.