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Obstetric & Gynaecology


 

 




Embryo

   

  • Embroyonic Stem Cell Lines Derived From Blastocysts

    Thomson JA, Itskovitz J, Shapiro SS, et al (Univ of Wisconsin, Madison)


    Science 282 : 1145 – 1147, 1998.


        


    Purpose. – Embryonic cell (ES) are embryo-derived, pluripotent mammalian cells that are capable of prolonged, undifferentiated proliferation and have the potential to form derivatives of all 3 embroyonic germ layers, even after prolonged culture. Studies of mouse ES cells suggest that they can contribute to wide range of adult tissues, including germ cells. Thus, ES cells may represent a new approach to introducing specific genetic changes into the germ line. 

       


    The pluripotent human ES cells were derived form human blastocysts. The resulting cell line was karyotypically normal, even after extended culture. They expressed high levels of telomerase activity.

      


    Editorial comment : The possibilities for in utero repair of neural tissue lost through injury, for replacing islet cells in embryos destined otherwise to become juvenile diabetics, or for repair of cardiomyopathy in utero become realizable.

        

      



 

 

Speciality Spotlight

 

 

Embryo
   

  • Embroyonic Stem Cell Lines Derived From Blastocysts
    Thomson JA, Itskovitz J, Shapiro SS, et al (Univ of Wisconsin, Madison)
    Science 282 : 1145 – 1147, 1998.
        
    Purpose. – Embryonic cell (ES) are embryo-derived, pluripotent mammalian cells that are capable of prolonged, undifferentiated proliferation and have the potential to form derivatives of all 3 embroyonic germ layers, even after prolonged culture. Studies of mouse ES cells suggest that they can contribute to wide range of adult tissues, including germ cells. Thus, ES cells may represent a new approach to introducing specific genetic changes into the germ line. 
       
    The pluripotent human ES cells were derived form human blastocysts. The resulting cell line was karyotypically normal, even after extended culture. They expressed high levels of telomerase activity.
      
    Editorial comment : The possibilities for in utero repair of neural tissue lost through injury, for replacing islet cells in embryos destined otherwise to become juvenile diabetics, or for repair of cardiomyopathy in utero become realizable.
        

      

 

By |2022-07-20T16:43:05+00:00July 20, 2022|Uncategorized|Comments Off on Embryo

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