Speciality
Spotlight

 




 

Obstetric & Gynaecology

 

 




Preterm Birth

   

  • Cervical dimensions and risk of preterm birth: A prospective cohort study. 

    K Hartmann, Jr.JM Thorp, TL McDonald et al (Univ of North Carolina, Chapel Hill, Wake Med Ctr, Raleigh, NC) Obstet Gynecol 93:504-509 (1999) Three articles are reviewed:

        


    Greater cervical dilatation and shorter length are associated with an increased risk of spontaneous preterm delivery in asymptomatic women at 24 – 29 weeks gestation.

       


    But one of the editors of the Year Book, Thomas H Kirschbaum comments that it is certain that 75% of the women with shortened cervices do not deliver prematurely. According Kirschbaum the strongest predictive relationship between abnormal cervical dimension in the second trimester is with premature PROM and not preterm birth.

        


    The next 2 articles of cervical length are from the King’s College Hosp Med School, London).

       

  • AL
    Stewart, et al (Univ College, London; Inst of
    Psychiatry, King’s College, London; Univ College
    London; et al)

    Brain Structure and Neurocognitive and
    Behavioural Function in Adolescents Who were Born
    Very Preterm. 


    Lancet 353: 1653-1657,1999.

        


    Background : Neonatal ultrasound can predict the
    neuro developmental outcomes of children born before
    33 weeks of gestation up to the age of 8 years.
    However, their later function is not well
    documented. The effects of very preterm birth on
    brain structure and neurocognitive and behavioural
    functioning in adolescence were investigated.

       


    Conclusion: Children born very preterm have an
    excess of neurocognitive and behavioral problems in
    adolescence. More than half of these adolescents had
    abnormal MRI brain scans.

        


    In the interest of providing perinatologists with
    solid information for predicting the long-term
    consequences of cranial ultrasound findings on
    infants born at or before 33 weeks gestational age,
    the authors provide us with their fifth review of
    follow-up data derived from MRI, this time conducted
    at a mean age of 14.9 years.

          


    Of the 72 infants born preterm, 55% had abnormal
    MRIs on follow-up and 42% were normal. Perinatal
    ultrasound therefore grossly underestimates the
    likelihood of abnormal MRI findings in the teen
    years. The results are not so clear with respect to
    cognitive and behavioral function. There was no
    clear relationship between brain structure and
    neurologic outcome.

        

  • W W Andrews, R L Goldenberg, et al for the National Institute of Child Health and
    Human Development Maternal-Fetal Medicine Units Network, Univ. of Alabama, Birmingham)

    The Preterm Prediction Study: Association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birth.

    Am J Obstet Gynecol, 2000; 183: 662-8

        


    Objective: This study was undertaken to determine the association between genitourinary tract infection with Chlamydia trachomatis and spontaneous preterm birth.

        


    Study Design: Genitourinary tract infection with C trachomatis was determined with a ligase chain reaction assay of voided urine samples collected at 24 weeks’ to 24 weeks 6 days gestation) and 28 weeks’ gestation (27 weeks’ to 28 weeks 6 days’ gestation). Case patients (spontaneous preterm birth at <37 weeks’ gestation; n=190) and control subjects (delivery at ³37 weeks’ gestation, matched for race, parity, and center; n-190) were selected from 2929 women enrolled in the Preterm Prediction Study of the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

       


    Conclusion: Genitourinary C trachomatis infection at 24 weeks’ gestation was associated with a 2-fold to 3-fold increased risk of subsequent spontaenous preterm birth.

  • W W Andrews, R L Goldenberg, et al for the National Institute of Child Health and Human Development Maternal-Fetal
    Medicine Units Network, Univ. of Alabama, Birmingham)

    The Preterm Prediction Study: Association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birth.

    Am J Obstet Gynecol, 2000; 183: 662-8



    Objective: This study was undertaken to determine the association between genitourinary tract infection with Chlamydia trachomatis and spontaneous preterm birth.



    Study Design: Genitourinary tract infection with C trachomatis was determined with a ligase chain reaction assay of voided urine samples collected at 24 weeks’ to 24 weeks 6 days gestation) and 28 weeks’ gestation (27 weeks’ to 28 weeks 6 days’ gestation). Case patients (spontaneous preterm birth at <37 weeks’ gestation; n=190) and control subjects (delivery at ³37 weeks’ gestation, matched for race, parity, and center; n-190) were selected from 2929 women enrolled in the Preterm Prediction Study of the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.



    Conclusion: Genitourinary C trachomatis infection at 24 weeks’ gestation was associated with a 2-fold to 3-fold increased risk of subsequent spontaenous preterm birth.

         

      



 

 

Speciality Spotlight

 

 

Preterm Birth
   

  • Cervical dimensions and risk of preterm birth: A prospective cohort study. 
    K Hartmann, Jr.JM Thorp, TL McDonald et al (Univ of North Carolina, Chapel Hill, Wake Med Ctr, Raleigh, NC) Obstet Gynecol 93:504-509 (1999) Three articles are reviewed:
        
    Greater cervical dilatation and shorter length are associated with an increased risk of spontaneous preterm delivery in asymptomatic women at 24 – 29 weeks gestation.
       
    But one of the editors of the Year Book, Thomas H Kirschbaum comments that it is certain that 75% of the women with shortened cervices do not deliver prematurely. According Kirschbaum the strongest predictive relationship between abnormal cervical dimension in the second trimester is with premature PROM and not preterm birth.
        
    The next 2 articles of cervical length are from the King’s College Hosp Med School, London).
       

  • AL Stewart, et al (Univ College, London; Inst of Psychiatry, King’s College, London; Univ College London; et al)
    Brain Structure and Neurocognitive and Behavioural Function in Adolescents Who were Born Very Preterm. 
    Lancet 353: 1653-1657,1999.
        
    Background : Neonatal ultrasound can predict the neuro developmental outcomes of children born before 33 weeks of gestation up to the age of 8 years. However, their later function is not well documented. The effects of very preterm birth on brain structure and neurocognitive and behavioural functioning in adolescence were investigated.
       
    Conclusion: Children born very preterm have an excess of neurocognitive and behavioral problems in adolescence. More than half of these adolescents had abnormal MRI brain scans.
        
    In the interest of providing perinatologists with solid information for predicting the long-term consequences of cranial ultrasound findings on infants born at or before 33 weeks gestational age, the authors provide us with their fifth review of follow-up data derived from MRI, this time conducted at a mean age of 14.9 years.
          
    Of the 72 infants born preterm, 55% had abnormal MRIs on follow-up and 42% were normal. Perinatal ultrasound therefore grossly underestimates the likelihood of abnormal MRI findings in the teen years. The results are not so clear with respect to cognitive and behavioral function. There was no clear relationship between brain structure and neurologic outcome.
        

  • W W Andrews, R L Goldenberg, et al for the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, Univ. of Alabama, Birmingham)
    The Preterm Prediction Study: Association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birth.
    Am J Obstet Gynecol, 2000; 183: 662-8
        
    Objective: This study was undertaken to determine the association between genitourinary tract infection with Chlamydia trachomatis and spontaneous preterm birth.
        
    Study Design: Genitourinary tract infection with C trachomatis was determined with a ligase chain reaction assay of voided urine samples collected at 24 weeks’ to 24 weeks 6 days gestation) and 28 weeks’ gestation (27 weeks’ to 28 weeks 6 days’ gestation). Case patients (spontaneous preterm birth at <37 weeks’ gestation; n=190) and control subjects (delivery at ³37 weeks’ gestation, matched for race, parity, and center; n-190) were selected from 2929 women enrolled in the Preterm Prediction Study of the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
       
    Conclusion: Genitourinary C trachomatis infection at 24 weeks’ gestation was associated with a 2-fold to 3-fold increased risk of subsequent spontaenous preterm birth.

  • W W Andrews, R L Goldenberg, et al for the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, Univ. of Alabama, Birmingham)
    The Preterm Prediction Study: Association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birth.
    Am J Obstet Gynecol, 2000; 183: 662-8

    Objective: This study was undertaken to determine the association between genitourinary tract infection with Chlamydia trachomatis and spontaneous preterm birth.

    Study Design: Genitourinary tract infection with C trachomatis was determined with a ligase chain reaction assay of voided urine samples collected at 24 weeks’ to 24 weeks 6 days gestation) and 28 weeks’ gestation (27 weeks’ to 28 weeks 6 days’ gestation). Case patients (spontaneous preterm birth at <37 weeks’ gestation; n=190) and control subjects (delivery at ³37 weeks’ gestation, matched for race, parity, and center; n-190) were selected from 2929 women enrolled in the Preterm Prediction Study of the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

    Conclusion: Genitourinary C trachomatis infection at 24 weeks’ gestation was associated with a 2-fold to 3-fold increased risk of subsequent spontaenous preterm birth.
         

      

 

By |2022-07-20T16:43:02+00:00July 20, 2022|Uncategorized|Comments Off on Preterm Birth

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